Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360836 | 0.91 | KRAS (0.54) | KRAS | |
| SCHEMBL21005684 | 0.91 | KRAS (0.48) | KRAS | |
| SCHEMBL25021059 | 0.91 | KRAS (0.54) | KRAS | |
| SCHEMBL19948987 | 0.87 | KRAS (0.74) | KRAS | |
| SCHEMBL19948988 | 0.87 | KRAS (0.74) | KRAS | |
| SCHEMBL21005636 | 0.86 | KRAS (0.53) | KRAS | |
| SCHEMBL19616516 | 0.86 | KRAS (0.59) | KRAS | |
| SCHEMBL21005311 | 0.85 | KRAS (0.48) | KRAS | |
| SCHEMBL19617176 | 0.85 | KRAS (0.59) | KRAS | |
| SCHEMBL19959320 | 0.85 | KRAS (0.54) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |