Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 10/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81410 | 0.92 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81770 | 0.90 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81406 | 0.83 | SLC22A2 (0.46) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL2679551 | 0.82 | SLC22A2 (0.46) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82243 | 0.81 | SLC22A2 (0.47) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82320 | 0.81 | SLC22A2 (0.44) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81826 | 0.81 | SLC22A2 (0.43) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL82744 | 0.81 | SLC22A2 (0.43) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL81809 | 0.81 | SLC22A2 (0.45) | SLC22A2CYP3A4TMEM97ABCG2 | |
| SCHEMBL86323 | 0.81 | SLC22A2 (0.49) | SLC22A2CYP3A4TMEM97ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045206-B2 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2023-02-15 | — | — | EP | disclosed |