Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.69 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447664 | 0.85 | CRBN (0.62) | CRBNDDB1 | |
| SCHEMBL21965813 | 0.85 | DDB1 (0.75) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL20595272 | 0.84 | DDB1 (0.73) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL25175945 | 0.84 | DDB1 (0.73) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL29744698 | 0.84 | DDB1 (0.73) | CRBNDDB1 | |
| SCHEMBL31312912 | 0.84 | CRBN (0.77) | CRBNDDB1 | |
| SCHEMBL30258516 | 0.83 | DDB1 (0.69) | CRBNDDB1 | |
| SCHEMBL25024363 | 0.82 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL25024446 | 0.82 | CRBN (0.70) | CRBNDDB1 | |
| SCHEMBL21965429 | 0.81 | CRBN (1.00) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-117794936-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023080732-A1 | COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF | 주식회사 유빅스테라퓨틱스 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023018237-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |