Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248547 | 1.00 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25027269 | 0.94 | KDM4E (0.44) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL30248710 | 0.94 | KDM4E (0.44) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL29227209 | 0.93 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL30248575 | 0.90 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25028045 | 0.90 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25027268 | 0.90 | MAPT (0.41) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL30248670 | 0.90 | MAPT (0.41) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL25028042 | 0.90 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER | |
| SCHEMBL29227011 | 0.90 | MAPT (0.48) | MAPTKDM4EALDH1A1HPGDGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |