Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248482 | 1.00 | MAPT (0.42) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL30248543 | 0.93 | MAPT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL30248507 | 0.93 | MAPT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL25028037 | 0.93 | MAPT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL30248681 | 0.93 | MAPT (0.44) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL25027261 | 0.91 | MAPT (0.42) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL30248593 | 0.91 | MAPT (0.42) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL29226901 | 0.91 | MAPT (0.45) | MAPTMEN1KMT2ATHRBKDM4E | |
| SCHEMBL29227209 | 0.90 | MAPT (0.48) | MAPTTHRBKDM4EGLAGFER | |
| SCHEMBL25027270 | 0.90 | MAPT (0.42) | MAPTMEN1KMT2ATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |