⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093318 | 0.77 | — | — | |
| SCHEMBL24322273 | 0.75 | — | — | |
| SCHEMBL22202240 | 0.75 | — | — | |
| SCHEMBL24367865 | 0.70 | — | — | |
| SCHEMBL24736096 | 0.65 | — | — | |
| SCHEMBL21982581 | 0.65 | — | — | |
| SCHEMBL20038202 | 0.65 | — | — | |
| SCHEMBL21533908 | 0.64 | — | — | |
| SCHEMBL22838559 | 0.64 | — | — | |
| SCHEMBL19215865 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045960-A1 | SUBSTITUTED HETEROAROMATIC PYRAZOLO-PYRIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-02-16 | — | — | US | disclosed |