Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.52 |
| ▸ | MET | P08581 | 6/20 | 0.52 |
| ▸ | TEK | Q02763 | 6/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.52 |
| ▸ | AURKA | O14965 | 4/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | RET | P07949 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.48 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028733 | 0.91 | KDR (0.52) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25028717 | 0.91 | PDGFRB (0.54) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25029467 | 0.88 | PDGFRB (0.49) | KDRMETTEKAURKBAURKA | |
| SCHEMBL27104765 | 0.88 | PDGFRB (0.49) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25029458 | 0.87 | PDGFRB (0.51) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25028726 | 0.86 | KDR (0.55) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25029466 | 0.86 | PDGFRB (0.48) | KDRMETTEKAURKBAURKA | |
| SCHEMBL27104764 | 0.86 | PDGFRB (0.53) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25028718 | 0.85 | PDGFRB (0.54) | KDRMETTEKAURKBAURKA | |
| SCHEMBL25028724 | 0.85 | KDR (0.54) | KDRMETTEKAURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016540-A1 | UREA MULTI-TARGET TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 上海爱博医药科技有限公司 | 2023-02-16 | — | — | WO | disclosed |
| WO-2023016543-A1 | UREA MULTI-TARGET TYROSINE KINASE INHIBITOR AND MULTIPLE MEDICAL APPLICATIONS THEREOF | 上海爱博医药科技有限公司 | 2023-02-16 | — | — | WO | disclosed |