Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364379 | 1.00 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL26719030 | 0.90 | BTK (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL29364621 | 0.90 | BTK (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL25028882 | 0.90 | BTK (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL29363431 | 0.86 | PIK3CD (0.47) | PIK3CDTBK1 | |
| SCHEMBL25211828 | 0.86 | PIK3CD (0.47) | PIK3CDTBK1 | |
| SCHEMBL25028663 | 0.85 | GSK3B (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL29363904 | 0.85 | GSK3B (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGNFATC1 | |
| SCHEMBL29364026 | 0.84 | DYRK1A (0.45) | NFATC1GSK3BDYRK1ATBK1 | |
| SCHEMBL25029046 | 0.84 | DYRK1A (0.45) | NFATC1GSK3BDYRK1ATBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | PIK3CD 4215/4885PIK3CA 4152/4885PIK3CB 3786/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | PIK3CD 4174/4885PIK3CA 4090/4885PIK3CB 3789/4885 |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | PIK3CD 4102/4885PIK3CA 4134/4885PIK3CB 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.