Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 11/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26321179 | 0.87 | CA1 (0.46) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL18534649 | 0.85 | CA1 (0.51) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL31450038 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL3096574 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL17494236 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL23314753 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL20326329 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL20334633 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL3096580 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL3083400 | 0.81 | CA1 (0.45) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |