Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.60 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30273820 | 1.00 | DDB1 (0.60) | DDB1CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL31731206 | 0.99 | DDB1 (0.59) | DDB1CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL31444618 | 0.99 | DDB1 (0.59) | DDB1CRBNIKZF2 | |
| SCHEMBL23541308 | 0.91 | DDB1 (0.61) | DDB1CRBNIKZF2 | |
| SCHEMBL31731531 | 0.85 | CRBN (0.57) | DDB1CRBNIKZF2 | |
| SCHEMBL20845742 | 0.85 | CRBN (0.71) | DDB1CRBNIKZF2 | |
| SCHEMBL24046327 | 0.82 | CRBN (0.64) | DDB1CRBN | |
| SCHEMBL22512346 | 0.82 | DDB1 (0.64) | DDB1CRBNIKZF2 | |
| SCHEMBL23845506 | 0.82 | CRBN (0.67) | DDB1CRBNIKZF2 | |
| SCHEMBL22502622 | 0.82 | CRBN (0.63) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |