Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597906 | 0.90 | TDP1 (0.57) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL27243560 | 0.85 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL27243556 | 0.85 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL20001957 | 0.85 | MEN1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL29974865 | 0.85 | MEN1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL15723437 | 0.85 | MEN1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL16234280 | 0.83 | MEN1 (0.54) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL4598805 | 0.82 | MEN1 (0.53) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL18085409 | 0.82 | MEN1 (0.66) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL20073977 | 0.81 | MEN1 (0.56) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017442-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |