Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | PTGFR | P43088 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274767 | 1.00 | HDAC1 (0.72) | HDAC1HDAC6MAPTRXFP1MTNR1A | |
| SCHEMBL9663074 | 1.00 | HDAC1 (0.72) | HDAC1HDAC6MAPTRXFP1MTNR1A | |
| SCHEMBL710937 | 1.00 | HDAC1 (0.72) | HDAC1HDAC6MAPTRXFP1MTNR1A | |
| SCHEMBL28188589 | 0.98 | HDAC1 (0.70) | HDAC1HDAC6MAPTRXFP1MTNR1A | |
| SCHEMBL1206248 | 0.98 | HDAC1 (0.70) | HDAC1HDAC6MAPTRXFP1MTNR1A | |
| Heptane SCHEMBL28189233 | 0.94 | PPARA (0.67) | HDAC1HDAC6MTNR1AMTNR1BPPARG | |
| SCHEMBL7758273 | 0.94 | HDAC1 (0.63) | HDAC1HDAC6MTNR1AMTNR1BPTGFR | |
| SCHEMBL29669893 | 0.94 | HDAC1 (0.63) | HDAC1HDAC6MTNR1AMTNR1BPTGFR | |
| SCHEMBL28189252 | 0.93 | PPARA (0.65) | HDAC1HDAC6MTNR1AMTNR1BPPARG | |
| SCHEMBL9663068 | 0.90 | HDAC1 (0.60) | HDAC1HDAC6MTNR1AMTNR1BPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017548-A1 | FUSED TETRACYCLIC COMPOUNDS, COMPOSITIONS AND DIAGNOSTIC APPLICATIONS THEREOF | BENAZIR J DR FATHIMA (IN) | 2023-02-16 | — | — | WO | disclosed |