Sulfacetamide

Sulfacetamide

SCHEMBL2503539

CC(=O)NS(=O)(=O)c1ccc(N)cc1.S

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfacetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.96
DHFR P00374 1/20 0.96
TSHR P16473 1/20 0.96
TDP1 Q9NUW8 1/20 0.96
ALDH1A1 P00352 2/20 0.64
MEN1 O00255 1/20 0.57
LMNA P02545 1/20 0.57
KMT2A Q03164 1/20 0.57
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
MMP1 P03956 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
MMP13 P45452 1/20 0.57
PKM P14618 2/20 0.54
CYP2C19 P33261 1/20 0.54
POLB P06746 1/20 0.54
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfacetamide SCHEMBL15869608 0.98 SMN1; SMN2 (0.93) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL28122264 0.98 SMN1; SMN2 (1.00) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL40863 0.98 SMN1; SMN2 (1.00) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL15567784 0.96 SMN1; SMN2 (0.89) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL3912378 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL29207414 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL28182511 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL23317 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL16097762 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1
Sulfacetamide SCHEMBL28308067 0.96 SMN1; SMN2 (0.96) SMN1; SMN2DHFRTSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022269665-A1 EXTERNAL PREPARATION マルホ株式会社 2022-12-29 WO disclosed
US-11045503-B2 Pharmaceutical composition for preventing, treating and curing rosacea, comprising snail slime, chamomile and propolis MUCIDERM S.A. (CL) 2021-06-29 US disclosed
US-20190336542-A1 SYNTHETIC BACTERIA AND METHODS OF USE SYMBIOME, INC. 2019-11-07 US disclosed
CN-108473528-A High intensity sweetner 赛诺米克斯公司 2018-08-31 CN disclosed
US-9944699-B2 In vitro method for identifying compounds of the Nav 1.9 sodium channel intended for the treatment of an inflammatory skin disease GALDERMA RESEARCH & DEVELOPMENT (FR) 2018-04-17 US disclosed
WO-2017185018-A1 SYNTHETIC BACTERIA AND METHODS OF USE NAKED BIOME, INC. (US) 2017-10-26 WO disclosed
US-20170281690-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING, TREATING AND CURING ROSACEA, COMPRISING SNAIL SLIME, CHAMOMILE AND PROPOLIS MUCIDERM S.A. (CL) 2017-10-05 US disclosed
US-20160340426-A1 MODULATORS OF THE NAV 1.9 SODIUM CHANNEL FOR TREATING AN INFLAMMATORY SKIN DISEASE AND DIAGNOSTIC METHODS UNIVERSITE D'AIX MARSEILLE (FR) 2016-11-24 US disclosed
US-20110240504-A1 METHOD AND APPARATUS FOR PACKAGING AND DISPENSING PHARMACEUTICALS APOTEX TECHNOLOGIES INC. (CA) 2011-10-06 US disclosed