Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035461 | 0.92 | POLB (0.38) | KDM4EPOLBKMT2AALDH1A1ATM | |
| SCHEMBL24962628 | 0.70 | — | — | |
| SCHEMBL1169615 | 0.67 | — | — | |
| SCHEMBL11507080 | 0.67 | — | — | |
| SCHEMBL3225586 | 0.67 | — | — | |
| SCHEMBL606668 | 0.67 | — | — | |
| SCHEMBL19249449 | 0.66 | POLB (0.37) | KDM4EPOLBKMT2AALDH1A1ATM | |
| SCHEMBL3582356 | 0.66 | POLB (0.40) | KDM4EPOLBKMT2AALDH1A1ATM | |
| SCHEMBL60409 | 0.64 | KDM4E (0.33) | KDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL6245109 | 0.64 | KDM4E (0.33) | KDM4EPOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |