Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30191265 | 1.00 | STING1 (0.44) | STING1KCNN4MAPTCLK1MEN1 | |
| SCHEMBL30191448 | 0.91 | MAPT (0.53) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL25035510 | 0.91 | MAPT (0.53) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL29256227 | 0.90 | STING1 (0.42) | STING1MAPTCLK1MEN1KMT2A | |
| SCHEMBL29256216 | 0.88 | MAPT (0.42) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL30191379 | 0.87 | MAPT (0.44) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL29256211 | 0.87 | MAPT (0.44) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL29256226 | 0.86 | MAPT (0.42) | STING1MAPTMEN1KMT2AHTT | |
| SCHEMBL29256219 | 0.86 | CCR3 (0.41) | MAPTCLK1MEN1KMT2AHTT | |
| SCHEMBL29256223 | 0.86 | USP2 (0.42) | MAPTCLK1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |