Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25034158 | 0.93 | ERN1 (0.46) | ERN1ALOX5APFEN1KITCTPS1 | |
| SCHEMBL25035373 | 0.91 | ERN1 (0.46) | ERN1ALOX5APFEN1KITCYP1A2 | |
| SCHEMBL25035576 | 0.90 | ERN1 (0.45) | ERN1ALOX5APFEN1KITCYP1A2 | |
| SCHEMBL25035637 | 0.88 | ERN1 (0.51) | ERN1CYP1A2CYP3A4MTORUSP2 | |
| SCHEMBL25035622 | 0.87 | ERN1 (0.46) | ERN1ALOX5APFEN1KITCYP1A2 | |
| SCHEMBL25035694 | 0.86 | ERN1 (0.51) | ERN1KITCYP1A2CYP3A4MTOR | |
| SCHEMBL25034244 | 0.86 | ERN1 (0.46) | ERN1ALOX5APFEN1CYP1A2CYP3A4 | |
| SCHEMBL25035642 | 0.85 | ERN1 (0.50) | ERN1KITCYP1A2CYP3A4MTOR | |
| SCHEMBL25035480 | 0.85 | ALOX5AP (0.48) | ERN1ALOX5APFEN1KITCYP1A2 | |
| SCHEMBL25035485 | 0.84 | ERN1 (0.48) | ERN1ALOX5APFEN1KITCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047209-A1 | PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AND METHODS OF USE | PARAZA PHARMA, INC. (CA) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047209-A1 | PYRIDO-PYRIMIDINONE AND PTERIDINONE COMPOUNDS AND METHODS OF USE | TYMP, TYMS, DPYD | ERN1 3167/4885ALOX5AP 1186/4885FEN1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.