Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882843 | 1.00 | STING1 (0.52) | STING1MAPTTP53SMN1; SMN2HDAC1 | |
| SCHEMBL23768825 | 0.93 | MAPT (0.54) | STING1MAPTTP53SMN1; SMN2 | |
| SCHEMBL29978613 | 0.93 | MAPT (0.54) | STING1MAPTTP53SMN1; SMN2 | |
| SCHEMBL30191367 | 0.91 | STING1 (0.52) | STING1MAPTTP53SMN1; SMN2HDAC1 | |
| SCHEMBL25037332 | 0.91 | STING1 (0.52) | STING1MAPTTP53SMN1; SMN2HDAC1 | |
| SCHEMBL25037356 | 0.88 | STING1 (0.52) | STING1MAPT | |
| SCHEMBL30191182 | 0.88 | STING1 (0.52) | STING1MAPT | |
| SCHEMBL30191346 | 0.87 | STING1 (0.46) | STING1MAPTKDR | |
| SCHEMBL29256218 | 0.87 | STING1 (0.46) | STING1MAPTKDR | |
| SCHEMBL25037325 | 0.86 | STING1 (0.46) | STING1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159535-A | Small molecule STING antagonists | 库拉德夫制药私人有限公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2023017451-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |