Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039041 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBL3MBTL1CNR2MEN1 | |
| SCHEMBL19592942 | 0.96 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBL3MBTL1CNR2MEN1 | |
| SCHEMBL20927022 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2POLBL3MBTL1MEN1KMT2A | |
| SCHEMBL22175881 | 0.82 | CNR2 (0.56) | SMN1; SMN2POLBL3MBTL1CNR2MEN1 | |
| SCHEMBL22920991 | 0.81 | CNR2 (0.54) | CNR2CNR1ALDH1A1 | |
| SCHEMBL16769060 | 0.81 | ESR1 (0.58) | CNR2KDM4ECNR1ALDH1A1 | |
| SCHEMBL20243874 | 0.81 | CNR2 (0.54) | CNR2CNR1ALDH1A1 | |
| SCHEMBL22921038 | 0.81 | CNR2 (0.54) | CNR2CNR1ALDH1A1 | |
| SCHEMBL20097921 | 0.81 | CNR2 (0.42) | CNR2GAACNR1 | |
| SCHEMBL26938838 | 0.81 | CNR2 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134076-A1 | THERAPY FOR INHIBITION OF SINGLE-STRANDED RNA VIRUS REPLICATION | Redhill Biopharma Ltd. (IL) | 2023-02-15 | — | — | EP | disclosed |