Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | KHK | P50053 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279292 | 1.00 | KDM4E (0.36) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL13462757 | 0.92 | KDM4E (0.35) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL13439151 | 0.92 | KDM4E (0.35) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL25039786 | 0.92 | KDM4E (0.35) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL11935409 | 0.92 | KDM4E (0.35) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL30279015 | 0.92 | KDM4E (0.35) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL13438928 | 0.92 | KDM4E (0.36) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL11935239 | 0.92 | KDM4E (0.36) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL13462796 | 0.92 | KDM4E (0.36) | KDM4EHTTPTGER4KHKUSP30 | |
| SCHEMBL30279042 | 0.91 | PTGER4 (0.36) | KDM4EPTGER4KHKLRRK2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016447-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-02-16 | — | — | WO | disclosed |