Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25040033 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25040104 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25041970 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25041853 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25041969 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25042487 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25042485 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25042466 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25040021 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 | |
| SCHEMBL25041877 | 1.00 | ESR1 (0.46) | ESR1ESR2LIMK1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-07-02 | — | — | US | disclosed |
| US-12024526-B2 | Fused polycyclic aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-07-02 | — | — | US | disclosed |
| US-20230047095-A1 | Fused Polycyclic Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024526-B2 | Fused polycyclic aromatic compound | AHR, PAH, H1-2 | ESR1 645/4885ESR2 255/4885LIMK1 4183/4885 |
| US-20230047095-A1 | Fused Polycyclic Aromatic Compound | AHR, PAH, H1-2 | ESR1 687/4885ESR2 220/4885LIMK1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.