SCHEMBL25045562

SCHEMBL25045562

CCP(=O)(CC)c1ncc(-n2ccn(-c3c4c(nn3-c3cc(C)c(F)c(C)c3)CCN(C)C4)c2=O)cc1NC

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25045951 0.89 GLP1R (0.34) GLP1R
SCHEMBL23749856 0.81 GLP1R (0.36) GLP1R
SCHEMBL25045683 0.77 GLP1R (0.36) GLP1R
SCHEMBL27254449 0.77 GLP1R (0.33) GLP1R
SCHEMBL25045563 0.72 GLP1R (0.37) GLP1R
SCHEMBL31692238 0.72 GLP1R (0.32) GLP1R
SCHEMBL31692185 0.72 GLP1R (0.36) GLP1R
SCHEMBL24599469 0.72 GLP1R (0.52) GLP1R
SCHEMBL25045686 0.70 GLP1R (0.36) GLP1R
SCHEMBL23748578 0.70 GLP1R (0.36) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023016546-A1 HETEROCYCLIC GLP-1 AGONISTS GASHERBRUM BIO, INC. (US) 2023-02-16 — — WO disclosed
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