Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 16/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047425 | 0.87 | PIP4K2A (0.39) | RIPK2PRMT5WDR77 | |
| SCHEMBL25047449 | 0.86 | RIPK2 (0.42) | RIPK2PRMT5WDR77MEN1 | |
| SCHEMBL25047466 | 0.86 | PRMT5 (0.42) | PRMT5WDR77MEN1 | |
| SCHEMBL25048378 | 0.86 | PRMT5 (0.45) | RIPK2PRMT5WDR77MEN1 | |
| SCHEMBL25047638 | 0.85 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL25049275 | 0.85 | PRMT5 (0.45) | PRMT5WDR77MEN1 | |
| SCHEMBL25047906 | 0.84 | PRMT5 (0.43) | PRMT5WDR77MEN1 | |
| SCHEMBL25048170 | 0.83 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL25046757 | 0.82 | PRMT5 (0.38) | RIPK2PRMT5WDR77MEN1 | |
| SCHEMBL25047434 | 0.81 | PRMT5 (0.43) | PRMT5WDR77MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |