Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 14/20 | 0.33 |
| ▸ | FLT3 | P36888 | 14/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 14/20 | 0.33 |
| ▸ | MERTK | Q12866 | 14/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941162 | 1.00 | AXL (0.33) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25048898 | 0.91 | AXL (0.33) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25047785 | 0.91 | MAP4K4 (0.31) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25047782 | 0.91 | CNR1 (0.34) | AXLFLT3TYRO3MERTKDRD2 | |
| SCHEMBL25047784 | 0.88 | AXL (0.30) | AXLFLT3TYRO3MERTKMAP4K4 | |
| SCHEMBL25048476 | 0.88 | C1S (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL30940812 | 0.88 | C1S (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL30940995 | 0.88 | C1S (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL25048576 | 0.88 | C1S (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL25047580 | 0.86 | MERTK (0.32) | MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |