SCHEMBL250503

SCHEMBL250503

CCCCCOc1cccc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 12/20 0.71
KCNA3 P22001 1/20 0.69
HTR1D P28221 3/20 0.68
SLC6A4 P31645 2/20 0.68
HRH1 P35367 1/20 0.65
CNR1 P21554 2/20 0.62
CNR2 P34972 2/20 0.62
CYP2C9 P11712 1/20 0.62
NR2E1 Q9Y466 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30516171 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL3696854 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL1681954 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL30516172 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL7616127 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL10589534 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL18551586 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL755688 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL20506760 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1
SCHEMBL9483628 0.98 HTR1B (0.69) HTR1BKCNA3HTR1DSLC6A4HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149819-B1 An improved process for acylation of naphthyl ethers COUNCIL SCIENT IND RES (IN) 2003-04-16 EP claimed
US-6320082-B1 REACTING NAPHTHYL ETHER WITH ACID ANHYDRIDE EMPLOYING SYNTHESIZED, MICROCRYSTALLINE, OR MICROCRYSTALLINE MODIFIED ZEOLITE BETA CATALYST IN NITROBENZENE AS SOLVENT, RECOVERING ACYL NAPHTHYL ETHERS BY CONVENTIONAL METHOD COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2001-11-20 US claimed
EP-1149819-A1 An improved process for acylation of naphthyl ethers Council of Scientific and Industrial Research (IN) 2001-10-31 EP claimed
EP-0656008-B1 THROMBIN RECEPTOR ANTAGONISTS COR THERAPEUTICS INC (US) 2000-03-15 EP claimed
US-5866681-A OLIGOPEPTIDES COR THERAPEUTICS, INC. (US) 1999-02-02 US claimed
JP-2675438-B2 1997-11-12 JP claimed
WO-1994003479-A1 THROMBIN RECEPTOR ANTAGONISTS COR THERAPEUTICS, INC. (US) 1994-02-17 WO claimed
CN-117063121-A Photosensitive film, photosensitive element, and method for producing laminate 株式会社力森诺科 2023-11-14 CN disclosed
CN-113166043-A Electrolyte for sulfur-based magnesium battery 富士胶片和光纯药株式会社 2021-07-23 CN disclosed
CN-107447371-B A kind of preparation method of high-strength temperature-resistant liquid crystal polymer spun-bonded non-woven fabrics 中原工学院 2019-12-03 CN disclosed
CN-107447363-B A kind of preparation method of the liquid crystal polymer melt spraying non-woven fabrics for high temperature filtration 中原工学院 2019-11-29 CN disclosed
CN-108780924-A Electrolyte containing magnesium ions 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
US-20180185325-A1 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME THESAN PHARMACEUTICALS, INC. (US) 2018-07-05 US disclosed
EP-0677519-A1 CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF Japan Tobacco Inc. (JP) 1995-10-18 EP disclosed
WO-1994003479-A1 THROMBIN RECEPTOR ANTAGONISTS COR THERAPEUTICS, INC. (US) 1994-02-17 WO disclosed
US-4692550-A Continuous process for thermal splitting of carbamic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0092738-B1 PROCESS FOR THE CONTINUOUS THERMAL DECOMPOSITION OF CARBAMIC-ACID ESTERS BAYER AG (DE) 1985-07-24 EP disclosed
US-4526722-A Manufacture of diacyloxy aromatic compounds ASHLAND OIL, INC. (US) 1985-07-02 US disclosed
EP-0092738-A1 Process for the continuous thermal decomposition of carbamic-acid esters BAYER AG (DE) 1983-11-02 EP disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180185325-A1 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME AHR, NR1H2, NR1H3 HTR1B 213/4885KCNA3 3417/4885HTR1D 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.