Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420630 | 0.89 | CYP2D6 (0.44) | CYP2D6ITGB3ITGA2BF2R | |
| SCHEMBL856649 | 0.89 | CYP2D6 (0.44) | CYP2D6ITGB3ITGA2BF2R | |
| SCHEMBL14155724 | 0.86 | CCR3 (0.44) | GFERSMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14559366 | 0.86 | CCR3 (0.44) | GFERSMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL17207607 | 0.86 | CCR3 (0.44) | GFERSMN1; SMN2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13436977 | 0.84 | TDP1 (0.55) | CYP2D6GFERSMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL4874313 | 0.84 | SMN1; SMN2 (0.40) | CYP2D6GFERSMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL19658450 | 0.83 | PREP (0.48) | CYP2D6GFERSMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL2706533 | 0.81 | KDM4E (0.46) | CYP2D6ALDH1A1EPHX2KDM4EEPHX1 | |
| SCHEMBL16494745 | 0.79 | CYP2D6 (0.50) | CYP2D6EPHX2EPHX1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018810-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |