Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Chenodiol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 known ✓ | Q96RI1 | 7/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 14/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 1.00 |
| ▸ | ENPP2 | Q13822 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 1.00 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chenodiol SCHEMBL22079588 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL24199134 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL23517166 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL22079179 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL25337643 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL24124587 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL25397934 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL24061005 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL23704676 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| Chenodiol SCHEMBL25337648 | 1.00 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 25707 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747627-A1 | METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS | Matterworks Inc (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122074420-A | Evaluation method of bile acid in relieving intestinal inflammation of east star spots | — | 2026-05-26 | — | — | CN | claimed |
| CN-122070276-A | Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same | 人类生物科学股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122060831-A | Method and device for generating ursodeoxycholic acid by continuous flow catalytic chenodeoxycholic acid | 南京师范大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122030504-A | Application of silybin combined chenodeoxycholic acid in improving quality degradation of procambarus clarkia caused by zero fish meal feed | 广东海洋大学 | 2026-05-15 | — | — | CN | claimed |
| US-20260131089-A1 | DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION FOR TREATMENT OF BINGE-EATING DISORDERS AND/OR OBESITY | APTARGROUP, INC. (US) | 2026-05-14 | — | — | US | claimed |
| EP-3869192-B1 | METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE | HUMAN METABOLOMICS INST INC (CN) | 2026-05-13 | — | — | EP | claimed |
| CN-122017068-A | Bile acid high-flux detection method based on ultra-high performance liquid chromatography tandem mass spectrometry and application thereof | 青岛百谱生物科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-4736862-A1 | COMPOSITION PROVIDING IMPROVED ORAL BIOAVAILABILITY OF DRUG AND METHOD THEREFOR | Hang Zhou Sciwind Biosciences Co., Ltd. (CN) | 2026-05-06 | — | — | EP | claimed |
| EP-4082552-B1 | LIQUIDS RICH IN NOBLE GAS AND METHODS OF THEIR PREPARATION AND USE | UNIV TEXAS (US) | 2026-05-06 | — | — | EP | claimed |
| US-4186143-A | Chenodeoxycholic acid recovery process | CANADA PACKERS LIMITED (CA) | 1980-01-29 | — | — | US | claimed |
| US-4185099-A | ANTIDANDRUFF AGENTS | Also Laboratori S.a.S. di Dr.P. Sorbini & C (IT) | 1980-01-22 | — | — | US | claimed |
| US-4163017-A | High purity chenodeoxycholic acid and method for obtaining same | DIAMALT AKTIENGESELLSCHAFT (DE) | 1979-07-31 | — | — | US | claimed |
| US-4140796-A | ANTIULCER | INTERX RESEARCH CORPORATION (US) | 1979-02-20 | — | — | US | claimed |
| US-4120959-A | Labile quaternary ammonium salts useful in binding bile acids in warm-blooded animals | INTERX RESEARCH CORPORATION (US) | 1978-10-17 | — | — | US | claimed |
| US-4079133-A | Safer method for dissolving gallstones combining hyodeoxycholic acid with chenodeoxycholic acids | WARREN-TEED LABORATORIES, INC. (US) | 1978-03-14 | — | — | US | claimed |
| US-4046899-A | Labile quaternary ammonium salts useful in binding bile acids in warm-blooded animals | INTERNX RESEARCH CORPORATION (US) | 1977-09-06 | — | — | US | claimed |
| US-3998859-A | Introducing Δ11 unsaturation into steroid compounds | EASTMAN KODAK COMPANY (US) | 1976-12-21 | — | — | US | claimed |
| US-3969503-A | STEROID | INTELLECTUAL PROPERTY DEVELOPMENT CORPORATION (US) | 1976-07-13 | — | — | US | claimed |
| US-3965131-A | Process for the purification of crude chenodeoxycholic acid | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-22 | — | — | US | claimed |