⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24751431 | 0.74 | — | — | |
| SCHEMBL20439663 | 0.72 | — | — | |
| SCHEMBL12799287 | 0.66 | — | — | |
| SCHEMBL19380479 | 0.66 | — | — | |
| SCHEMBL20663318 | 0.65 | — | — | |
| SCHEMBL24942282 | 0.63 | — | — | |
| SCHEMBL21393842 | 0.63 | — | — | |
| SCHEMBL24942281 | 0.62 | — | — | |
| SCHEMBL24514891 | 0.62 | — | — | |
| SCHEMBL1820210 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-B1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS INC (US) | 2023-02-22 | — | — | EP | disclosed |