Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 9/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25061055 | 1.00 | APP (0.40) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061027 | 0.96 | ESR1 (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061093 | 0.96 | ESR1 (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061063 | 0.96 | ESR1 (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061125 | 0.96 | APP (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061058 | 0.96 | APP (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061086 | 0.96 | APP (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061148 | 0.94 | APP (0.48) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061012 | 0.93 | APP (0.42) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL25061109 | 0.93 | APP (0.42) | APPHSD17B1HSD17B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056339-A1 | Condensed Polycyclic Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056339-A1 | Condensed Polycyclic Aromatic Compound | PAH, AHR, HRH4 | APP 2218/4885HSD17B1 2787/4885HSD17B2 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.