Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25061355 | 0.98 | MEN1 (0.33) | PTGS2PDK2ESR1KDM4EMEN1 | |
| SCHEMBL25061358 | 0.92 | PDK2 (0.34) | PTGS2PDK2ESR1KDM4EMEN1 | |
| SCHEMBL20466618 | 0.91 | MEN1 (0.36) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL15290145 | 0.91 | MEN1 (0.36) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL16922920 | 0.91 | MEN1 (0.36) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL16922922 | 0.91 | MEN1 (0.36) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL22403340 | 0.90 | PDK2 (0.34) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL22151230 | 0.90 | MEN1 (0.39) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL17804996 | 0.90 | MEN1 (0.39) | PDK2ESR1KDM4EMEN1LMNA | |
| SCHEMBL17903067 | 0.90 | MEN1 (0.39) | PDK2ESR1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058635-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |