SCHEMBL2506147

SCHEMBL2506147

CC=C[Si](C)(C)CCN1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
HRH3 Q9Y5N1 6/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
KCNH2 Q12809 1/20 0.32
LTA4H P09960 2/20 0.32
KDM4E B2RXH2 1/20 0.32
SLC6A3 Q01959 1/20 0.31
PSMB1 P20618 2/20 0.31
PSMB5 P28074 2/20 0.31
PSMB2 P49721 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2506146 1.00 CARM1 (0.35) CARM1PRMT6PRMT8HRH3TDP1
SCHEMBL2505458 0.98 HRH3 (0.38) CARM1PRMT6PRMT8HRH3CYP1A2
SCHEMBL2505460 0.98 HRH3 (0.38) CARM1PRMT6PRMT8HRH3CYP1A2
SCHEMBL27821059 0.96 CARM1 (0.31) CARM1PRMT6PRMT8HRH3
SCHEMBL2509253 0.91
SCHEMBL2509252 0.91
SCHEMBL27821056 0.88 HRH3 (0.41) HRH3KCNH2
SCHEMBL2503312 0.86 HRH3 (0.45) HRH3L3MBTL1CYP1A2KCNH2KDM4E
SCHEMBL2503308 0.86 HRH3 (0.45) HRH3L3MBTL1CYP1A2KCNH2KDM4E
SCHEMBL27820889 0.84 HRH3 (0.37) HRH3L3MBTL1KCNH2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304488-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-06 US disclosed
US-20110245408-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-10-06 US disclosed
CN-102206304-A Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL CO 2011-10-05 CN disclosed