Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 4/20 | 0.72 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.72 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.72 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.72 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.72 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.72 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.72 |
| ▸ | PRKDC | P78527 | 2/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.72 |
| ▸ | RET | P07949 | 1/20 | 0.72 |
| ▸ | NQO2 | P16083 | 1/20 | 0.72 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.72 |
| ▸ | FECH | P22830 | 1/20 | 0.72 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.72 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.72 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.72 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.72 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.72 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.72 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25064801 | 1.00 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL25064667 | 0.96 | MTOR (0.67) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23251945 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23150523 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23251817 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23252071 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL24519470 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23251676 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23158079 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL23158000 | 0.95 | MTOR (0.72) | MTORRICTORRPTORMAPKAP1MLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055672-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055672-A1 | C40-, C28-, and C-32-Linked Rapamycin Analogs as mTOR Inhibitors | MTOR, RICTOR, RPTOR | MTOR 1/4885RICTOR 2/4885RPTOR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.