SCHEMBL250676

SCHEMBL250676

CCCCCn1cccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.56
RAB9A P51151 7/20 0.56
HTT P42858 6/20 0.56
LMNA P02545 3/20 0.56
APOBEC3A P31941 2/20 0.56
APOBEC3G Q9HC16 2/20 0.56
ALDH1A1 P00352 2/20 0.56
PABPC1 P11940 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.54
MAPK1 P28482 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
HSP90AA1 P07900 3/20 0.54
GALR3 O60755 2/20 0.54
POLB P06746 2/20 0.54
ATM Q13315 2/20 0.54
MAPT P10636 2/20 0.54
KDM4E B2RXH2 1/20 0.54
RAD52 P43351 1/20 0.54
PAX8 Q06710 1/20 0.54
NR2F2 P24468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5599875 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5601944 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL1792913 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5603811 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5602339 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5604253 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5602162 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
Fluoride SCHEMBL18438900 0.97 NPC1 (0.54) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL562381 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A
SCHEMBL5601524 0.97 NPC1 (0.57) NPC1RAB9AHTTLMNAAPOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117623839-A Biaryl axis chiral pyrrole compound and synthesis method and application thereof 华中师范大学 2024-03-01 CN claimed
CN-117603139-A Preparation method of 1- (hetero) aryl-2- (sulfonyl) -1,2,3,4 tetrahydroisoquinoline compound 遵义医科大学 2024-02-27 CN claimed
CN-114380730-B Method for synthesizing N-aryl pyrrole and N-aryl indole by denitration coupling of nitroarene 广西大学 2023-12-05 CN claimed
CN-116574043-A Preparation method of 2, 5-dimethyl-N-aryl pyrrole 浙江工业大学 2023-08-11 CN claimed
CN-115974804-A Synthesis process of novel arylpyrrole compound pesticide 内蒙古莱科作物保护有限公司 2023-04-18 CN claimed
CN-115572258-A C 2 Preparation method of axial chiral biquinoline framework compound 中国科学院成都有机化学有限公司 2023-01-06 CN claimed
CN-115403523-A Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
CN-115403522-A Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof 中国科学院成都有机化学有限公司 2022-11-29 CN claimed
CN-114920752-A Aza-condensed distorted polycyclic aromatic hydrocarbon semiconductor material and preparation method and application thereof 南京邮电大学 2022-08-19 CN claimed
CN-112430205-B Preparation method of arylpyrrole compound 湖南海利常德农药化工有限公司 2022-06-21 CN claimed
EP-0216289-A1 Poly-N-acyl-pyrroles and producing method BAYER AG (DE) 1987-04-01 EP claimed
US-4617228-A PRECIPITATING AND DOPING POLYPYRROLES IN POROUS MATERIAL; STRONG OXIDANT AND NON-NUCLEOPHILIC ANIONS ROCKWELL INTERNATIONAL CORPORATION (US) 1986-10-14 US claimed
EP-0099984-B1 ELECTRICALLY CONDUCTIVE PYRROLE COPOLYMERS AND PROCESS FOR THEIR PREPARATION BASF Aktiengesellschaft (DE) 1986-09-10 EP claimed
US-4582575-A Electrically conductive composites and method of preparation ROCKWELL INTERNATIONAL CORPORATION (US) 1986-04-15 US claimed
US-4568483-A CATIONIC COPOLYMERS WITH HETEROCYCLIC COMONOMERS, MECHANICAL PROPEETIES BASF AKTIENGESELLSCHAFT (DE) 1986-02-04 US claimed
US-4567250-A POLYMERIZATION IN PRESENCE OF CONDUCTIVE SALT BASF AKTIENGESELLSCHAFT (DE) 1986-01-28 US claimed
EP-0055358-B1 ELECTROCONDUCTIVE POLYPYRROLE DERIVATIVES BASF Aktiengesellschaft (DE) 1984-06-27 EP claimed
EP-0099984-A1 Electrically conductive pyrrole copolymers and process for their preparation BASF Aktiengesellschaft (DE) 1984-02-08 EP claimed
US-4401545-A COMPLEXED WITH NITRO-AROMATIC COMPOUND BASF AKTIENGESELLSCHAFT (US) 1983-08-30 US claimed
US-4001249-A CYCLOCOUPLING N-ACYLPYRROLE AND A,A*-HALOGENOKETONE, REDUCING AGENTS SANWA KAGAKU KENKYUSHO CO. LTD. (JA) 1977-01-04 US claimed