Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 1.00 |
| ▸ | CCND3 | P30281 | 5/20 | 1.00 |
| ▸ | GSK3B | P49841 | 5/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.82 |
| ▸ | CDK2 | P24941 | 10/20 | 0.82 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.82 |
| ▸ | PIM1 | P11309 | 4/20 | 0.81 |
| ▸ | MTOR | P42345 | 3/20 | 0.80 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | CCNK | O75909 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.63 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25068538 | 0.90 | CCNA2 (0.83) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068503 | 0.90 | CCNA2 (1.00) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068525 | 0.90 | CCNA2 (0.84) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068536 | 0.90 | CDK4 (1.00) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068497 | 0.89 | CCNA2 (1.00) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068207 | 0.88 | CCNA2 (1.00) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068526 | 0.87 | CCNA2 (1.00) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068486 | 0.87 | CCNA2 (0.82) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL25068517 | 0.86 | CDK4 (0.82) | CDK4CCND3GSK3BCCNA2CDK2 | |
| SCHEMBL29761384 | 0.86 | CDK4 (0.82) | CDK4CCND3GSK3BCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820753-B2 | Inhibitors of bacterial pasta kinases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820753-B2 | Inhibitors of bacterial pasta kinases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-20230060122-A9 | INHIBITORS OF BACTERIAL PASTA KINASES | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820753-B2 | Inhibitors of bacterial pasta kinases | SBK3, MAP3K3, MAP4K3 | CDK4 575/4885CCND3 533/4885GSK3B 563/4885 |
| US-20230060122-A9 | INHIBITORS OF BACTERIAL PASTA KINASES | SBK3, MAP3K3, MAP4K3 | CDK4 575/4885CCND3 533/4885GSK3B 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.