⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2509865 | 1.00 | — | — | |
| SCHEMBL3544488 | 1.00 | — | — | |
| SCHEMBL420563 | 1.00 | — | — | |
| SCHEMBL285502 | 1.00 | — | — | |
| SCHEMBL3544171 | 1.00 | — | — | |
| SCHEMBL3546851 | 0.69 | — | — | |
| SCHEMBL3069176 | 0.69 | — | — | |
| SCHEMBL3068798 | 0.69 | — | — | |
| SCHEMBL3067693 | 0.69 | — | — | |
| SCHEMBL3550713 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664214-B2 | Small molecule potentiators of metabotropic glutamate receptors I | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-03-04 | — | — | US | disclosed |
| US-8314120-B2 | Small molecule potentiators of metabotropic glutamate receptors | ABBOTT GMBH & CO. KG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-20110245247-A1 | NOVEL SMALL MOLECULE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2011-10-06 | — | — | US | disclosed |
| US-20110245232-A1 | NOVEL SMALL MOLECULE POTENTIATORS OF METABOTROPIC GLUTAMATE RECEPTORS I | ABBOTT GMBH & CO. KG (DE) | 2011-10-06 | — | — | US | disclosed |