Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.76 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20688297 | 0.86 | TYK2 (1.00) | TYK2JAK1 | |
| SCHEMBL22342875 | 0.83 | TYK2 (0.94) | TYK2JAK1 | |
| SCHEMBL29746827 | 0.83 | TYK2 (0.94) | TYK2JAK1 | |
| SCHEMBL20688268 | 0.82 | TYK2 (1.00) | TYK2 | |
| SCHEMBL22343305 | 0.80 | TYK2 (0.83) | TYK2 | |
| SCHEMBL20688296 | 0.80 | TYK2 (0.83) | TYK2 | |
| SCHEMBL22343299 | 0.78 | TYK2 (0.86) | TYK2 | |
| SCHEMBL21778906 | 0.76 | TYK2 (0.67) | TYK2 | |
| SCHEMBL21726966 | 0.76 | TYK2 (0.67) | TYK2 | |
| SCHEMBL21963053 | 0.76 | TYK2 (0.76) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056447-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056447-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | TYK2 1/4885JAK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.