SCHEMBL2507539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2501396	0.94	WEE1 (0.55)	EGFRTNK2FLT3KCNH2AXL
	SCHEMBL2480201	0.90	KCNH2 (0.58)	EGFRTNK2FLT3KDRLCK
	SCHEMBL2501565	0.89	KCNH2 (0.56)	EGFRTNK2KDRLCKSRC
	SCHEMBL2503488	0.87	TNK2 (0.56)	EGFRTNK2FLT3KDRLCK
	SCHEMBL12197654	0.87	TNK2 (0.54)	EGFRTNK2FLT3KDRLCK
	SCHEMBL2502950	0.87	LCK (0.59)	EGFRTNK2FLT3KDRLCK
	SCHEMBL2507027	0.87	KCNH2 (0.50)	EGFRTNK2FLT3KDRLCK
	SCHEMBL2481647	0.86	LCK (0.50)	EGFRTNK2FLT3KDRLCK
	SCHEMBL2506456	0.85	EGFR (0.54)	EGFRTNK2FLT3KCNH2AXL
	SCHEMBL2501526	0.85	LCK (0.52)	EGFRTNK2FLT3KDRLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.