SCHEMBL2507724

SCHEMBL2507724

Clc1cccnc1-c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
LMNA P02545 4/20 0.54
CCR1 P32246 3/20 0.54
CCR5 P51681 3/20 0.54
CCR8 P51685 3/20 0.54
CYP1A2 P05177 1/20 0.54
POLB P06746 1/20 0.54
METAP1 P53582 1/20 0.54
BLM P54132 1/20 0.54
HIF1A Q16665 1/20 0.54
DOHH Q9BU89 1/20 0.54
P4HTM Q9NXG6 1/20 0.54
NPC1 O15118 5/20 0.46
RAB9A P51151 4/20 0.46
TP53 P04637 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALOX15 P16050 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17783297 0.88 GRM5 (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28361381 0.87 GRM5 (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5966404 0.87 KDM4E (0.64) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7793959 0.85 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29652637 0.83 GRM5 (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30339992 0.82 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2306238 0.81 DPP4 (0.48) KDM4ELMNACCR1CCR8METAP1
SCHEMBL29652596 0.80 GRM5 (0.44) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7553182 0.79 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2306242 0.79 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676555-A1 MOLECULAR LINKERS CWAN Technologies Pty Ltd (AU) 2026-01-14 EP claimed
WO-2024182840-A1 MOLECULAR LINKERS CWAN Technologies Pty Ltd (AU) 2024-09-12 WO claimed
US-20110245503-A1 ENANTIOSELECTIVE SYNTHESIS OF ASYMMETRIC BETA-CARBOLINE INTERMEDIATES UNIVERSIDAD DE TALCA (CL) 2011-10-06 US claimed
CN-101607213-A Palladium coordination polymer molecule aggregate catalysis material and its production and use UNIV FUDAN (CN) 2009-12-23 CN claimed
EP-4676555-A1 MOLECULAR LINKERS CWAN Technologies Pty Ltd (AU) 2026-01-14 EP disclosed
WO-2024182840-A1 MOLECULAR LINKERS CWAN Technologies Pty Ltd (AU) 2024-09-12 WO disclosed
CN-109843867-B Novel compounds and their use for detecting target molecules in a sample 日内瓦大学 2022-11-15 CN disclosed
CN-110317573-A Composition for polishing and its manufacturing method and magnetic grinding method 福吉米株式会社 2019-10-11 CN disclosed
CN-107935919-B The preparation method of 2,2 '-bipyridyls of one kind and its derivative 南京红太阳生物化学有限责任公司 2019-09-03 CN disclosed
CN-104423170-B Photosensitive polysiloxane composition, protective film and assembly with protective film 奇美实业股份有限公司 2019-05-24 CN disclosed
CN-109557764-A Chemically amplified positive photosensitive resin composition, resist pattern and method for forming the same, and electronic device 奇美实业股份有限公司 2019-04-02 CN disclosed
CN-109503466-A Organic compound, display panel, and display device 武汉天马微电子有限公司 2019-03-22 CN disclosed
WO-2009122148-A1 FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS UCB PHARMA S.A. (BE) 2009-10-08 WO disclosed
WO-2009071895-A1 FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2009-06-11 WO disclosed
WO-2009071890-A1 TRICYCLIC KINASE INHIBITORS UCB PHARMA S.A. (BE) 2009-06-11 WO disclosed
EP-2029570-A1 FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS UCB Pharma S.A. (BE) 2009-03-04 EP disclosed
WO-2007141504-A1 FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2007-12-13 WO disclosed
CN-1083435-C Polymer containing conjugated N-fluoropyridinium salt and use thereof DAIKIN IND LTD (JP) 2002-04-24 CN disclosed
CN-1277193-A Polymer containing conjugate N-fluoro pyridinium salt and its use DAIKIN IND LTD (JP) 2000-12-20 CN disclosed
CN-1161691-A Polymer containing conjugated N-fluoropyridinium salt and use thereof DAIKIN IND LTD (JP) 1997-10-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245503-A1 ENANTIOSELECTIVE SYNTHESIS OF ASYMMETRIC BETA-CARBOLINE INTERMEDIATES PDE1B, PDE3B, PDE1A KDM4E 3331/4885LMNA 2336/4885CCR1 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.