SCHEMBL250794

SCHEMBL250794

[CH2]CC([CH2])(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10635 0.74
SCHEMBL84482 0.70
SCHEMBL82374 0.70
SCHEMBL477607 0.70
SCHEMBL13274824 0.67
SCHEMBL16930146 0.67
SCHEMBL2865176 0.67
SCHEMBL6832917 0.67
SCHEMBL12005028 0.67
SCHEMBL475047 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680054-B2 Bronchodilating hetero-linked amides ARCEDE PHARMA AB (SE) 2023-06-20 US disclosed
EP-3818055-B1 NOVEL BRONCHODILATING HETERO-LINKED AMIDES RESPIRATORIUS AB PUBL (SE) 2022-02-16 EP disclosed
US-20210139455-A1 NOVEL BRONCHODILATING HETERO-LINKED AMIDES ARCEDE PHARMA AB (SE) 2021-05-13 US disclosed
EP-3818055-A1 NOVEL BRONCHODILATING HETERO-LINKED AMIDES Respiratorius AB (Publ) (SE) 2021-05-12 EP disclosed
EP-3548475-B1 SULFONAMIDE ANALOGUES OF GALIELLALACTONE GLACTONE PHARMA DEV AB (SE) 2021-03-03 EP disclosed
US-10781197-B2 Sulfonamide analogues of galiellalactone GLACTONE PHARMA DEVELOPMENT AB (SE) 2020-09-22 US disclosed
US-20200087274-A1 SULFONAMIDE ANALOGUES OF GALIELLALACTONE GLACTONE PHARMA DEVELOPMENT AB (SE) 2020-03-19 US disclosed
WO-2020009653-A1 NOVEL BRONCHODILATING HETERO-LINKED AMIDES RESPIRATORIUS AB (PUBL) (SE) 2020-01-09 WO disclosed
EP-3548475-A1 SULFONAMIDE ANALOGUES OF GALIELLALACTONE Glactone Pharma Development AB (SE) 2019-10-09 EP disclosed
US-10351577-B2 Ether analogues of galiellalactone GLACTONE PHARMA DEVELOPMENT AB (SE) 2019-07-16 US disclosed
WO-2009007419-A1 NOVEL BRONCHODILATING ISOQUINOLINE CARBAMATES RESPIRATORIUS AB (SE) 2009-01-15 WO disclosed
WO-2009007418-A1 NOVEL BRONCHODILATING ISOQUINOLINE AMIDES RESPIRATORIUS AB (SE) 2009-01-15 WO disclosed
WO-2009007420-A1 NOVEL BRONCHODILATING ALPHA, BETA-UNSATURATED ISOQUINOLINE AMIDES RESPIRATORIUS AB (SE) 2009-01-15 WO disclosed
EP-1981883-A1 NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES AstraZeneca AB (SE) 2008-10-22 EP disclosed
WO-2008108730-A1 NOVEL 2-HETEROARYL SUBSTITUTED BENZOTHIOPHENES AND BENZOFURANES 709 ASTRAZENECA AB (SE) 2008-09-12 WO disclosed
WO-2008108729-A1 NOVEL 2-HETEROARYL SUBSTITUTED INDOLES 695 ASTRAZENECA AB (SE) 2008-09-12 WO disclosed
US-20080221149-A1 2-[6-(methylamino)pyridin-3-yl]-1-benzofuran-5-ol; for imaging amyloid deposits in living patients ASTRAZENECA AB (SE) 2008-09-11 US disclosed
US-20080027051-A1 Novel Heteroaryl Substituted Benzoxazoles ASTRAZENECA AB (SE) 2008-01-31 US disclosed
WO-2007149030-A1 NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES ASTRAZENECA AB (SE) 2007-12-27 WO disclosed
WO-2007086800-A1 NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES ASTRAZENECA AB (SE) 2007-08-02 WO disclosed