Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 12/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 5/20 | 0.43 |
| ▸ | CCR7 | P32248 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079861 | 0.89 | CCR6 (0.48) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079539 | 0.87 | CCR6 (0.47) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079839 | 0.87 | CCR6 (0.48) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079808 | 0.85 | CCR6 (0.47) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079480 | 0.84 | CCR6 (0.46) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079822 | 0.84 | CCR6 (0.70) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL30284900 | 0.84 | CCR6 (0.70) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079533 | 0.84 | CCR6 (0.45) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079879 | 0.84 | SYK (0.45) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079851 | 0.83 | CCR6 (0.48) | CCR6CCNKCCNA2CDK2CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023534-A2 | ARYL SULFONYL COMPOUNDS AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |