Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080270 | 0.88 | MTOR (0.48) | MTORATRATRIPPIK3CARPTOR | |
| SCHEMBL24811649 | 0.83 | ATR (0.44) | MTORATRATRIPPIK3CA | |
| SCHEMBL24809858 | 0.83 | ATR (0.45) | MTORATRATRIPPIK3CARPTOR | |
| SCHEMBL25080287 | 0.80 | ATR (0.43) | MTORPDE2AATRATRIPPIK3CA | |
| SCHEMBL24811148 | 0.80 | PDE2A (0.48) | MTORPDE2AATRATRIP | |
| SCHEMBL24811116 | 0.79 | ATR (0.44) | MTORATRATRIPPIK3CA | |
| SCHEMBL25080301 | 0.76 | MTOR (0.46) | MTORPDE2AATRATRIPPIK3CA | |
| SCHEMBL25080627 | 0.76 | MTOR (0.46) | MTORPDE2AATRATRIPPIK3CA | |
| SCHEMBL25287138 | 0.76 | ATR (0.61) | MTORATRATRIPPIK3CA | |
| SCHEMBL25287137 | 0.76 | ATR (0.61) | MTORATRATRIPPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |