Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 18/20 | 0.50 |
| ▸ | ATRIP | Q8WXE1 | 16/20 | 0.50 |
| ▸ | MTOR | P42345 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080698 | 0.84 | ATR (0.68) | ATRATRIPMTORLCKNUAK1 | |
| SCHEMBL25080690 | 0.84 | ATR (0.68) | ATRATRIPMTORLCKNUAK1 | |
| SCHEMBL25080796 | 0.83 | HRH3 (0.45) | ATRATRIPMTORLCK | |
| SCHEMBL25080710 | 0.83 | HRH3 (0.45) | ATRATRIPMTORLCK | |
| SCHEMBL25080574 | 0.83 | HRH3 (0.47) | ATRATRIPMTOR | |
| SCHEMBL25791094 | 0.83 | ATR (0.44) | ATRATRIPMTORPIK3CACHEK1 | |
| SCHEMBL25790786 | 0.82 | ATR (0.64) | ATRATRIPMTORLCKNUAK1 | |
| SCHEMBL24810137 | 0.82 | ATR (0.46) | ATRATRIPMTORLCKCHEK1 | |
| SCHEMBL25080336 | 0.81 | ATR (0.49) | ATRATRIPMTORLCKNUAK1 | |
| SCHEMBL25080341 | 0.81 | ATR (0.49) | ATRATRIPMTORLCKNUAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |