Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.48 |
| ▸ | ATR | Q13535 | 10/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 8/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292440 | 0.90 | MTOR (0.48) | MTORATRATRIPPIK3CAPIK3CD | |
| SCHEMBL25243745 | 0.90 | MTOR (0.48) | MTORATRATRIPPIK3CAPIK3CD | |
| SCHEMBL25080340 | 0.82 | ATR (0.64) | MTORATRATRIPPIK3CA | |
| SCHEMBL1611443 | 0.82 | MTOR (0.53) | MTORATRPIK3CAPIK3R1PIK3CD | |
| SCHEMBL1611445 | 0.82 | MTOR (0.53) | MTORATRPIK3CAPIK3R1PIK3CD | |
| SCHEMBL2673181 | 0.82 | MTOR (0.53) | MTORATRPIK3CAPIK3R1PIK3CD | |
| SCHEMBL25080284 | 0.79 | MTOR (0.50) | MTORATRPIK3CAPIK3CDCHEK1 | |
| SCHEMBL25080274 | 0.79 | MTOR (0.50) | MTORATRPIK3CAPIK3CDCHEK1 | |
| SCHEMBL25235943 | 0.79 | MTOR (0.57) | MTORATRPIK3CAPIK3R1PIK3CD | |
| SCHEMBL1612230 | 0.79 | MTOR (0.57) | MTORATRPIK3CAPIK3R1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |