Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 14/20 | 0.63 |
| ▸ | MTOR | P42345 | 9/20 | 0.63 |
| ▸ | ATRIP | Q8WXE1 | 5/20 | 0.63 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.63 |
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.63 |
| ▸ | PRKDC | P78527 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 14/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244279 | 0.92 | ATR (0.74) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25789858 | 0.92 | ATR (0.74) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25790196 | 0.90 | ATR (0.62) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25790242 | 0.90 | ATR (0.62) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25287637 | 0.90 | ATR (0.62) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25789471 | 0.90 | ATR (0.62) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25789630 | 0.88 | ATR (0.59) | ATRMTORATRIPNUAK1LCK | |
| SCHEMBL25790962 | 0.86 | ATR (0.63) | ATRMTORPDCD1CD274CHEK1 | |
| SCHEMBL25790888 | 0.86 | ATR (0.63) | ATRMTORPDCD1CD274CHEK1 | |
| SCHEMBL25080241 | 0.85 | ATR (0.85) | ATRMTORATRIPNUAK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761804-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| WO-2023116594-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海安诺达生物科技有限公司 | 2023-06-29 | — | — | WO | disclosed |
| CN-116283960-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |