Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.83 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | RAF1 | P04049 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191161 | 1.00 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25081184 | 1.00 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30254106 | 1.00 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25079245 | 0.99 | KRAS (0.85) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25079262 | 0.98 | KRAS (0.82) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30597690 | 0.98 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25079406 | 0.98 | KRAS (0.83) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25402010 | 0.94 | KRAS (0.86) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25401994 | 0.94 | KRAS (0.86) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25081646 | 0.94 | KRAS (0.74) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020519-A1 | 1, 4-OXAZEPANE DERIVATIVES AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-23 | — | — | WO | disclosed |