Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAP3K12 | Q12852 | 12/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DLK1 | P80370 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082114 | 1.00 | PDE10A (0.45) | PDE10AMAP3K12MAP3K7ADKCHRNA7 | |
| SCHEMBL25082120 | 1.00 | PDE10A (0.45) | PDE10AMAP3K12MAP3K7ADKCHRNA7 | |
| SCHEMBL25082160 | 0.87 | MAP3K12 (0.46) | PDE10AMAP3K12CHRNA7KCNH2 | |
| SCHEMBL25082132 | 0.87 | MAP3K12 (0.45) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL25082121 | 0.87 | MAP3K12 (0.45) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL25082103 | 0.87 | MAP3K12 (0.45) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL15743920 | 0.77 | MAP3K12 (0.50) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL15743911 | 0.77 | MAP3K12 (0.50) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL25147712 | 0.77 | MAP3K12 (0.50) | MAP3K12MAP3K7ADKDLK1SOS1 | |
| SCHEMBL25082387 | 0.76 | ATR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020512-A1 | SUBSTITUTED PYRIDINE ANALOGUE, PREPARATION METHOD THEREFOR, AND USE THEREOF AS AHR MODULATOR | 成都奥睿药业有限公司 | 2023-02-23 | — | — | WO | disclosed |