⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187980 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL15706017 | 0.63 | — | — | |
| SCHEMBL4185099 | 0.60 | — | — | |
| SCHEMBL4980571 | 0.60 | — | — | |
| SCHEMBL16716205 | 0.60 | — | — | |
| SCHEMBL3809324 | 0.60 | — | — | |
| SCHEMBL19411556 | 0.60 | — | — | |
| SCHEMBL670761 | 0.60 | — | — | |
| SCHEMBL25476022 | 0.58 | NPSR1 (0.31) | — | |
| Sulfamate SCHEMBL285371 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |