Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 0.66 |
| ▸ | CDK4 | P11802 | 19/20 | 0.66 |
| ▸ | CSF1R | P07333 | 19/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.66 |
| ▸ | CCNK | O75909 | 3/20 | 0.66 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.66 |
| ▸ | CDK2 | P24941 | 3/20 | 0.66 |
| ▸ | CDK7 | P50613 | 3/20 | 0.66 |
| ▸ | CDK9 | P50750 | 3/20 | 0.66 |
| ▸ | CCNH | P51946 | 3/20 | 0.66 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.66 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21267740 | 0.95 | CDK4 (0.58) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267160 | 0.92 | CSF1R (0.76) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267320 | 0.88 | CDK6 (0.85) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267074 | 0.85 | CSF1R (0.57) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267030 | 0.82 | CDK6 (0.76) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267071 | 0.81 | CSF1R (0.74) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267807 | 0.81 | CSF1R (0.72) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21245722 | 0.79 | CSF1R (1.00) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21245812 | 0.79 | CDK6 (1.00) | CDK6CDK4CSF1RPIK3CDCCNK | |
| SCHEMBL21267321 | 0.78 | CDK6 (0.89) | CDK6CDK4CSF1RPIK3CDCCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | CDK6 2/4885CDK4 1/4885CSF1R 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.