SCHEMBL2508657

SCHEMBL2508657

CC(C#N)C(C)(O)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697019 0.77
SCHEMBL12515118 0.77
SCHEMBL1605756 0.77
SCHEMBL11641828 0.77
SCHEMBL17935769 0.71 TSHR (0.39)
SCHEMBL2992474 0.71
SCHEMBL17935613 0.71 TSHR (0.39)
Dimethylketone Cyanohydrin SCHEMBL28204579 0.71 TSHR (0.56)
SCHEMBL15209462 0.69 TSHR (0.44)
SCHEMBL20111211 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634409-B1 OREXIN RECEPTOR ANTAGONISTS BENEVOLENTAI BIO LTD (GB) 2021-04-07 EP disclosed
US-20200190090-A1 OREXIN RECEPTOR ANTAGONISTS BENEVOLENTAI BIO LIMITED (GB) 2020-06-18 US disclosed
EP-3634409-A1 OREXIN RECEPTOR ANTAGONISTS Benevolentai Bio Limited (GB) 2020-04-15 EP disclosed
WO-2020016117-A1 METHOD FOR PRODUCING OLIGOMERIC POLYISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2020-01-23 WO disclosed
WO-2020016118-A1 METHOD FOR PRODUCING OLIGOMERIC POLYISOCYANATES WITH SUBSEQUENT FRACTIONAL LIQUID-LIQUID EXTRACTION COVESTRO DEUTSCHLAND AG (DE) 2020-01-23 WO disclosed
WO-2020016119-A1 METHOD FOR OLIGOMERIZING ISOCYANATES BY MEANS OF POLYHEDRAL SILSESQUIOXANE CATALYSTS COVESTRO DEUTSCHLAND AG (DE) 2020-01-23 WO disclosed
WO-2020016120-A1 METHOD FOR PRODUCING OLIGOMERIC COMPOUNDS BY FRACTIONAL EXTRACTIVE REACTION COVESTRO DEUTSCHLAND AG (DE) 2020-01-23 WO disclosed
WO-2018206959-A1 OREXIN RECEPTOR ANTAGONISTS BENEVOLENTAI BIO LIMITED (GB) 2018-11-15 WO disclosed
WO-2018206956-A1 OREXIN RECEPTOR ANTAGONISTS BENEVOLENTAI BIO LIMITED (GB) 2018-11-15 WO disclosed
EP-2174937-B1 Synthesis process of polyol carbonate from polyols, conducted in using a solvent selective for polyols carbonates ARKEMA FRANCE (FR) 2015-04-15 EP disclosed
US-8877948-B2 Synthesis process of polyol carbonate from polyols, conducted in using a solvent selective for polyols carbonates ARKEMA FRANCE (FR) 2014-11-04 US disclosed
US-20110245513-A1 SYNTHESIS PROCESS OF POLYOL CARBONATE FROM POLYOLS, CONDUCTED IN USING A SOLVENT SELECTIVE FOR POLYOLS CARBONATES ARKEMA FRANCE (FR) 2011-10-06 US disclosed
EP-2174937-A1 Synthesis process of polyol carbonate from polyols, conducted in using a solvent selective for polyols carbonates ARKEMA FRANCE (FR) 2010-04-14 EP disclosed
US-7601747-B1 One-pot process for making di-functional di-tetrazole diols to produce tetrazole based polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-10-13 US disclosed
US-7528257-B1 Process for making di-functional tetrazole diols to produce tetrazole base polymers NAVY, UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE 2009-05-05 US disclosed
EP-0872475-B1 Inhibiting formation of foulants in acrylonitrile manufacture or recovery NALCO EXXON ENERGY CHEM LP (US) 2003-10-22 EP disclosed
EP-0872475-A2 Inhibiting formation of foulants in acrylonitrile manufacture or recovery NALCO/EXXON ENERGY CHEMICALS, L.P. (US) 1998-10-21 EP disclosed