SCHEMBL250889

SCHEMBL250889

FC1=C(F)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460010 0.72
SCHEMBL8024784 0.71
SCHEMBL3628766 0.67
SCHEMBL17911607 0.60
SCHEMBL10276 0.57
SCHEMBL22689491 0.51
SCHEMBL42968 0.51 GRIN2D (0.33)
SCHEMBL1445443 0.50
Hydrochloric Acid SCHEMBL4178849 0.46 GRIN2D (0.31)
Methane SCHEMBL23044967 0.38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115353514-B Fluoro-pyridopyrimidinone compounds and synthesis method thereof 河南师范大学 2023-07-25 CN claimed
CN-115353514-A Fluoro-pyridopyrimidone compound and synthetic method thereof 河南师范大学 2022-11-18 CN claimed
CN-113200926-B Method for modifying 2-aryl quinazoline-4 (3H) -ketone compound 四川大学 2022-09-23 CN claimed
CN-113480476-B 4-fluoropyridine derivative and preparation method and application thereof 山东师范大学 2022-07-22 CN claimed
CN-113200926-A Method for modifying 2-aryl quinazoline-4 (3H) -ketone compound 四川大学 2021-08-03 CN claimed
CN-120647497-A Method for synthesizing gem-difluoro cyclopropane by rhodium-catalyzed asymmetric hydrogenation of gem-difluoro cyclopropene 大连理工大学 2025-09-16 CN disclosed
CN-120647497-A Method for synthesizing gem-difluoro cyclopropane by rhodium-catalyzed asymmetric hydrogenation of gem-difluoro cyclopropene 大连理工大学 2025-09-16 CN disclosed
CN-119852519-A Electrolyte additive, electrolyte containing same and lithium ion secondary battery 株式会社村田制作所 2025-04-18 CN disclosed
CN-119852520-A Electrolyte additive, electrolyte containing same and lithium ion secondary battery 株式会社村田制作所 2025-04-18 CN disclosed
CN-119591507-A Gem-difluorocyclopentane compounds and methods of synthesizing the same 南通大学 2025-03-11 CN disclosed
CN-115353514-B Fluoro-pyridopyrimidinone compounds and synthesis method thereof 河南师范大学 2023-07-25 CN disclosed
CN-115353514-B Fluoro-pyridopyrimidinone compounds and synthesis method thereof 河南师范大学 2023-07-25 CN disclosed
US-7897823-B2 Process for production of azeotrope compositions comprising hydrofluoroolefin and hydrogen fluoride and uses of said azeotrope compositions in separation processes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-01 US disclosed
EP-1960336-A1 PROCESSES FOR PRODUCTION AND PURIFICATION OF HYDROFLUOROOLEFINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-08-27 EP disclosed
US-20080018230-A1 Layered Product, Luminescence Device and Use Thereof ZEON CORPORATION (JP) 2008-01-24 US disclosed
WO-2007053178-A1 PROCESSES FOR PRODUCTION AND PURIFICATION OF HYDROFLUOROOLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-10 WO disclosed
EP-1745922-A1 MULTILAYER BODY, LIGHT-EMITTING DEVICE AND USE THEREOF ZEON CORPORATION (JP) 2007-01-24 EP disclosed
US-20060106263-A1 Processes for production and purification of hydrofluoroolefins THE CHEMOURS COMPANY FC, LLC 2006-05-18 US disclosed
EP-0680341-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1995-11-08 EP disclosed
WO-1994016739-A1 PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS SONUS PHARMACEUTICALS, INC. (US) 1994-08-04 WO disclosed