SCHEMBL25089596

SCHEMBL25089596

c1ccc(-c2ccc(N(c3ccc(-c4cccc5ccccc45)cc3)c3ccc4cc(-c5cccc6c5ccc5ccccc56)ccc4c3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
PPARG P37231 9/20 0.39
PPARA Q07869 9/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
PPARD Q03181 1/20 0.39
HPRT1 P00492 1/20 0.38
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
TNF P01375 1/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25088782 0.95 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL25088793 0.95 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL26054829 0.94 CA12 (0.45) MCL1ACMSDCA12CA1CA2
SCHEMBL20313392 0.94 MCL1 (0.48) MCL1ACMSDCA12CA1CA2
SCHEMBL25089235 0.94 MCL1 (0.41) MCL1ACMSDCA12CA1CA2
SCHEMBL25088785 0.93 CA12 (0.42) MCL1ACMSDCA12CA1CA2
SCHEMBL27048644 0.93 MCL1 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL21123704 0.93 CA12 (0.47) MCL1ACMSDCA12CA1CA2
SCHEMBL21123700 0.93 CA12 (0.47) MCL1ACMSDCA12CA1CA2
SCHEMBL23805395 0.93 MCL1 (0.42) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023027173-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-03-02 WO disclosed